PREGNANCY CARDS

This card test is for the detection of β hCG in urine which is an indicator for pregnancy.
1. Human chorionic gonadotropin, hCG belongs to the family of glycoprotein hormone. It consists of two non-identical subunits the alpha and beta subunits. The beta subunit of hCG due to the unique amino acid sequence is structurally different from that of other hormones like LH, FSH, and TSH. This renders the beta subunits its biological and immunological specificity.
2. The hCG is produced by the developing placental tissue after implantation of the fertilized ovum in the uterine wall. Hence its level being to rise and becomes detectable in urine as early as 5 to 10 days after conception and reaches up to 100 IU/mL during the first trimester.
3. Thus the detection of hCG in urine acts as an excellent tool for the confirmation of pregnancy in normal females. However, the urine hCG
the level is also found to rise in the case of trophoblastic or non-trophoblastic neoplasm like hydatiform mole and choriocarcinoma condition.